“Researchers experienced MRNA-vaccine mice, designed to protect against several different coronaviruses, including not only SARS-COV-2 and its mutations, but also related viruses that could potentially cause pandemic in the future. The new vaccine contains the structure of the structure Hybrid thicoid proteins that combine the features of various coronaviruses. ” This is reported by the German Focus magazine (Translation INOPRESSA.RU).
“SARS-COV-2 coronavirus vaccines are aimed at the colors of the virus, which is a specific structure on the surface of the virus, which allows it to penetrate the cells, and also serves as a recognition marker for the immune system, explains the publication. – Since in The resulting mutations of thicoid proteins are changing, there is a fear that the available vaccines can be less effective against new virus options. “
“Team of scientists under the leadership of David Martineza from the University of North Carolina … used the same principle on which the current MRNA-vaccines from PFizer / Biontech and Moderna were based on the body: they provide the body with a genetic scheme of the colil-shaped protein form RNA, on the basis of which cell cells produce proteins in order to develop the immune system of the corresponding antibodies. “
“However, instead of providing the body to the body of the structure of one type of spit-shaped protein, Martinez and its colleagues were used hybrid proteins – a combination of components of spit-shaped proteins of different coronaviruses. So, one of such hybrids combined the characteristics of SARS-COV-COV proteins. 2, the causative agent of the current Pandemic COVID-19, as well as SARS-COV, which caused the first Pandemic atypical pneumonia in 2003, and coronavirus bats, which may be transmitted to people in the future. “
“Mice that received a new combination vaccine produced functional antibodies both against SARS-COV and SARS-COV-2, and against the volatile mouse virus. When after completing the immunization, they were influenced by viruses, they did not get sick, but in their pulmonary The fabric did not have any damage. These mice were also protected from SARS-COV-2 mutations, in particular, the South African version, “the article says.
“Our results promising for the future, as they suggest that we can develop more universal pancorn-breed vaccines for proactive protection against viruses … – says Martinez. – With this strategy, we may be able to prevent the appearance of SARS-COV -3 “- transfers Focus.