Nobel Prize laureate in chemistry, the famous Turkish scientist Aziz Sanjar conducted a study of a new method of treating brain tumors, writes Turkish Daily Sabah.
Sanjar and his colleagues studied the 5-ethyl-2′-deoxyuridine molecules, an analogue of Timidin-one of the components of natural DNA. EDU is used by molecular biologists in experiments on the study of DNA synthesis in the dividing cells of the nervous system and is a toxic substance for cells, including cancer.
“It was known that the EDU molecule has a moderately toxic effect, but the mechanism of this was unknown. Now we found out exactly how it kills the cage. There used to be data that Edu killed cancer cells, but it is strange that no one was behind these results Watched, ”said Sanjar.
Scientists placed living cells with intact DNA on the environment containing Edu. According to Sanjar, he and his colleagues gave unexpected results. Edu constantly launched the “repair” process of DNA, as if it were damaged. As a result, the cells could not cope with the continuously income signals about the need to “repair” DNA and died.
The authors of the study believe that this will help to develop a new way of eliminating cells of cancer tumors. The study will be published in the new issue of ProCeeDings of the National Academy of Sciences (PNAS), an interdisciplinary scientific journal in the USA.